Association between IL 37 gene variants (rs4241122 and rs2723186) and Graves disease risk

Introduction: Graves Disease (GD) is the most common cause of primary hyperthyroidism. It an autoimmune disorder characterized by presence thyrotropin related antibodies that stimulate thyroidal cells, resulting in overproduction thyroid hormones. has been reported cytokines might be involved GD pathogenesis. So, aim present study was to investigate possible associations between IL-37 Single Nucleotide Polymorphisms (SNPs) and susceptibility GD.